. Beta-blockers reduce cerebral (brain) blood flow by directly acting on the blood vessels in the brain.
Vasodilation (widening of the blood vessels) is associated with migraines. They induce a change in the electrical activity of the brain, preventing an effect described as cortical spreading depression—a type of slow brain activity associated with the early stages of migraine. These medications may also increase activity in the hypothalamus, a region of the brain that has been associated with migraines.
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It is also used to treat or prevent heart attack, and to reduce the severity and frequency of migraine headaches. Hemangeol (propranolol oral liquid 4.28 milligrams) is given to infants who are at least 5 weeks old to treat a genetic condition called infantile hemangiomas. Hemangiomas are caused by blood vessels grouping together in an abnormal.